You can bring defragging down to the simple machine, where everything is stored. Check your servers for capacity and workload. You can simply apply the same procedures and rules as defragging a single server. But keep in mind that your SAN structure might rely on availability of some servers, so scheduling defragging should be done carefully! Some defraggers watch the computers activity and adjust their resource usage accordingly. This might be a very good idea for your situation!
This was first published in February 2002