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I am currently running NT 4.0 server. We use this server for everything including MS Exchange. Can it be upgraded to 2003 and the most current version of Exchange without problems?
"Without problems" ... hmmm. The conversion from NT 4.0 to Windows 2000 is not one to take lightly. The upgrade has some real ramifications on how the enterprise works. Upgrading Exchange 5.5 to 2003 is not straightforward either. Normally I would suggest getting another server, doing an NT DC upgrade, installing Exchange 2003, then migrating the Exchange information. Finally, retiring the old system. If this is not a possibility -- I would make sure that you have a good and well-tested backup and restore process.