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Do you have users that struggle to change a directory once they FTP to your server? Here is a way to put them in the correct directory by default.
First, set up a directory structure with the folder names identical to the log in username. Then, set your NTFS file permissions so that the users only have access to their own folder name. Point the FTP root to the level above their folder (i.e. all folders reside in 'Users' and point FTP root to 'Users').