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You can turn this off only for individual users, not at a machine level. You do this in this manner:
1. Set the "macro security" to the level you want it for each application in Office 2003.
2. Find the HKEY_CURRENT_USER\software\Microsoft\office11.0 folder in your registry.
3. Export that registry folder and all the keys in it to your desktop.
4. After making all your other changes to the settings in those applications, save the settings with the "save my settings" wizard in the Microsoft Office Tools location on your start menu.
5. Now when you install Office 2003 on a new computer you can restore those settings from the saved settings and will save a bunch of time.
IMPORTANT NOTE: Restoring from saved settings will automatically reset the macro security level for all programs to "high." This is where that registry key comes in. Run the exported key to set up your security settings again after you restore the settings through the wizard.
Also, if you are rolling out many new computers with Office 2003, do the above tasks to a test user and save that user's profile over the default user in the document's and settings folder. Don't forget to set permission to everyone. Then image the computer using Norton Ghost. Now you won't have to run the wizard or the registry key for each user you set up on the imaged computer.
This was first published in September 2005