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Are there any issues with an Exchange 5.5 server on a Windows 2000 network in native mode?

Are there any issues with an Exchange 5.5 server on a Windows 2000 network in native mode? This Exchange 5.5 server has ServicePack 4 installed and is the only Exchange server on the network. Any guidance will be appreciated.
Exchange 5.5 SP4 should work fine on W2K SP1. The mode of the domain (native vice mixed) doesn't make a difference. Are you having a problem?

One thing. Don't run Exchange on a domain controller. Both Exchange 5.5 and Active Directory use LDAP, and you'll get problems if you run them both on the same machine.

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