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Is there a registry setting that will stop users from storing profiles on local machines?

I would like to know if there is a registry setting that will stop users from storing a profile on the local machine. I manage the computers in a high school and there are too many profiles on the computers in the lab. Without deleting these manually or writing a script to do this, the only other way would be to have a registry setting to prevent all the profiles. Is there such a setting?
To delete cached roaming profiles each time a user logs off, follow the directions of Knowledge Base document Q274152.

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