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Prevent a user from sending e-mail outside of the office

Is there a way that you can prevent a user from sending e-mail outside of the office? We often want to do this in cases where an employee has resigned. We still want them to be able to receive e-mail and send internal e-mail, but we don't want them to be able to send e-mail outside the office. As a former Lotus Notes administrator, I used to be able to do that, but I'm not sure how to do this in Exchange. Thanks.
On the Default SMTP Virtual Server for each Exchange server, you have the ability to control the 'Permission for Submit and Relay' via the Authentication Properties page. You can configure permissions for individual users or groups. For this to work correctly, you must disable 'Anonymous Authentication.' Therefore, these settings can only be configured on Exchange servers that are not configured to be SMTP connectors to the Internet. For more info see Microsoft KB article 818778, Users without permissions to relay messages can still send messages through the SMTP virtual server.

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Related information from SearchExchange.com:

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  • Reference Center: Permissions and passwords

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